Genetic structure of human populations II. Differentiation of blood group gene frequencies among isolated populations
نویسندگان
چکیده
منابع مشابه
Genetic differentiation of blood polymorphic systems among three isolated human populations in central Japan.
An isolate population, which more or less genetically deviates from neighboring populations, sometimes comprises subpopulations with different gene frequency distributions within it. It is not always easy to, however, assess the degree of genetic diversity among subpopulations. Choosing small isolated population, on which biological, demographic, historical, and marital data are relatively easy...
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We studied human population structure using genotypes at 377 autosomal microsatellite loci in 1056 individuals from 52 populations. Within-population differences among individuals account for 93 to 95% of genetic variation; differences among major groups constitute only 3 to 5%. Nevertheless, without using prior information about the origins of individuals, we identified six main genetic cluste...
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Received August 5, I966. * Caylor-Nickel Clinic and Foundation, Bluffton, Indiana. t University of Michigan, Ann Arbor, Michigan. $ Mackay Memorial Hospital, Taipei, Taiwan. § American Mission, Box I, Bahrain, Arabian Gulf. principally of Swiss extraction. The effective population size is not known, but the level of inbreeding is extremely high. The population appears to deviate from random mat...
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The Jewish diaspora can be viewed as a natural process in population dispersion and differentiation. We extend genetic studies on the Jewish diaspora to an analysis of human leukocyte antigen (HLA) haplotype distributions in the Jewish peoples, and show the value of this information for the design of Jewish marrow donor registries. HLA data from the Hadassah Bone Marrow Registry having parental...
متن کاملThe Distribution of Gene Frequencies in Populations.
The effects of the various evolutionary factors-mutation, cross breeding,. selection and inbreeding-can be reduced to common terms by considering the rates of change which they tend to bring about in the relative frequencies of alleles.' In the absence of such factors, there is constancy of gene frequencies from the symmetry of the Mendelian mechanism. The frequency (q) of a given gene changes ...
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ژورنال
عنوان ژورنال: Heredity
سال: 1966
ISSN: 0018-067X,1365-2540
DOI: 10.1038/hdy.1966.17